Sukkur is a central hub of many small and large scale industries. Among significant industries are cotton textiles, tobacco, pharmaceuticals, paint and varnish, cement, leather, hand pumps, sugar, rice-husking, agriculture implements and lock making. Small-scale cottage industry contains boat making, thread ball spooling, cutlery, hosiery, fishing accessories, trunk making brass-wares and ceramics.
Sukkur had a rich fertile and cultivable land place until some few decades before, when the Indus River was not too barren as today. Now, its productivity of agriculture has been lessened. It has not acquired a suitable yield per unit are over time, on the aspect of sustained shortages of water and avoidance of modern irrigation networks. In spite, the deficiency of water, during the time of kharif, rice, bajra, cotton, tomatoes and peas are cultivated; while during the time of Rabi the primary crops are barley, graham, wheat and melon. Sukkur is popular, world over, for its tasty dates. Sukkur also has a huge Riveraine, forest along the course side of Indus. These beautiful tropical forests are discovered within the secured embankments on either area of the Indus. During the years of 1997-98, the total place under the forests was 510 km2 which produced and yielded 55,000 cubic feet of timber and 27,000 cubic feet of firewood besides the other mine materials.